An ancient plant. A modern renaissance.
A succulent plant native to the Cape Provinces of South Africa. For millennia, the indigenous San and Khoikhoi peoples fermented and chewed this remarkable plant—they called it kougoed, meaning "chewable thing."[1,2]
An empathogen. A mood-elevator. A social lubricant.
100% sober. Zero hangover.
For millennia, the San (Bushmen) and Khoikhoi peoples of South Africa chewed fermented kanna during long hunts, spiritual rituals, and social gatherings.[1]
Dutch colonist Jan van Riebeeck documents kanna use, noting locals consumed it daily for mood elevation and to dispel fear.[2]
Cape Governor Simon van der Stel records detailed observations of kanna preparation during his expedition inland.[3]
Swedish botanist Carl Thunberg records how the Khoikhoi fermented and prepared kanna, introducing it to the scientific world.[4]
Meiring conducts the first phytochemical study, identifying the presence of alkaloids in Sceletium tortuosum.[5]
fMRI studies confirm kanna's effects on the amygdala, validating centuries of traditional use with modern neuroscience.[6]
Kanna emerges as a natural alternative for mood enhancement and connection—no hangover required.
How kanna works its magic
Kanna blocks the reabsorption of serotonin, leaving more of this 'feel-good' neurotransmitter available in your brain.[7]
→ More serotonin = elevated moodInhibits phosphodiesterase-4, an enzyme linked to inflammation and cognitive function. This may enhance focus and reduce anxiety.[7,8]
→ Clearer thinking, calmer mindPromotes the release of monoamines (including serotonin and dopamine) from neurons, amplifying mood-lifting effects.[9]
→ Natural euphoria, heart-openingThe Star Player
The most abundant and active alkaloid. Potently inhibits serotonin reuptake (Ki 1.4 nM), keeping more feel-good serotonin available in your brain.[7]
The Dual Agent
Works double duty—both serotonin reuptake inhibition AND PDE4 inhibition. This combo may explain kanna's unique anxiolytic effects.[7,8]
The Supporter
A mesembrine alcohol that contributes to the entourage effect, working synergistically with other alkaloids.[10]
The Balancer
Helps modulate the overall alkaloid profile, contributing to kanna's gentle, balanced effects.[5]
Promotes feelings of well-being and euphoria
Enhances social bonding and empathy
Reduces cortisol and calms the nervous system
Social lubrication without the hangover
Supports focus and mental flexibility
Completely legal across the United States
Unlike many substances, kanna has a reverse tolerance. The more you take it, the more sensitive you become to its effects. Many people find they need to "prime" their system over 3-5 days before the magic really clicks.[5]
Start gentle. Build the relationship.
That's when the heart opens.
We're here to help you feel with psychoactive plants + mushrooms ahead of legalization.
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